Publikationen von Sarah E. O’Connor

Stander, E. A.; Cuello, C.; Birer-Williams, C.; Kulagina, N.; Jansen, H.; Carqueijeiro, I.; Méteignier, L.-V.; Vergès, V.; Oudin, A.; Papon, N. et al.; Dirks, R.; Jensen, M. K.; O’Connor, S. E.; de Bernonville, T. D.; Besseau, S.; Courdavault, V.: The Vinca minor genome highlights conserved evolutionary traits in monoterpene indole alkaloid synthesis. G3: Genes, Genomes, Genetics 12 (12), jkac268 (2022)

Langley, C.; Tatsis, E. E.; Hong, B.; Nakamura, Y.; Paetz, C.; Stevenson, C. E. M.; Basquin, J.; Lawson, D. M.; Caputi, L.; O’Connor, S. E.: Expansion of the catalytic repertoire of alcohol dehydrogenases in plant metabolism. Angewandte Chemie, International Edition in English 61 (48), e202210934 (2022)

Cuello, C.; Stander, E. A.; Jansen, H. J.; Dugé De Bernonville, T.; Lanoue, A.; Giglioli-Guivarch, N.; Papon, N.; Dirks, R. P.; Jensen, M. K.; O’Connor, S. E. et al.; Bessau, S.; Courdavault, V.: Genome assembly of the medicinal plant Voacanga thouarsii. Genome Biology and Evolution 14 (11), evac158 (2022)

Kamileen, M. O.; DeMars II, M. D.; Hong, B.; Nakamura, Y.; Paetz, C.; Lichman, B. R.; Sonawane, P. D.; Caputi, L.; O’Connor, S. E.: Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in Pseudo-Aspidosperma alkaloid biosynthesis. Journal of the American Chemical Society 144 (43), S. 19673 - 19579 (2022)

Palmer, L.; Chuang, L.; Siegmund, M.; Kunert, M.; Yamamoto, K.; Sonawane, P. D.; O’Connor, S. E.: In vivo characterization of key iridoid biosynthesis pathway genes in catnip (Nepeta cataria). Planta 256 (5), 99 (2022)

Köllner, T. G.; David, A.; Luck, K.; Beran, F.; Kunert, G.; Zhou, J.-J.; Caputi, L.; O’Connor, S. E.: Biosynthesis of iridoid sex pheromones in aphids. Proceedings of the National Academy of Sciences of the United States of America 119 (42), e2211254119 (2022)

Dudley, Q. M.; Jo, S.; Serna Guerrero, D. A.; Chhetry, M.; Smedley, M. A.; Harwood, W. A.; Sherden, N. H.; O’Connor, S. E.; Caputi, L.; Patron, N. J.: Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineered Nicotiana benthamiana. Communications Biology 5, 949 (2022)

Zhang, J.; Hansen, L. G.; Gudich, O.; Viehrig, K.; Lassen, L. M. M.; Schrübbers, L.; Adhikari, K. B.; Rubaszka, P.; Carrasquer-Alvarez, E.; Chen, L. et al.; D’Ambrosio, V.; Lehka, B.; Haidar, A. K.; Nallapareddy, S.; Giannakou, K.; Laloux, M.; Arsovska, D.; Jørgensen, M. A. K.; Chan, L. J. G.; Kristensen, M.; Christensen, H. B.; Sudarsan, S.; Stander, E. A.; Baidoo, E.; Petzold, C. J.; Wulff, T.; O’Connor, S. E.; Courdavault, V.; Jensen, M. K.; Keasling, J. D.: A microbial supply chain for production of the anti-cancer drug vinblastine. Nature 609, S. 341 - 347 (2022)

Hernández-Lozada, N. J.; Hong, B.; Wood, J. C.; Caputi, L.; Basquin, J.; Chuang, L.; Kunert, M.; Rodriguez Lopez, C. E.; Langley, C.; Zhao, D. et al.; Buell, C. R.; Lichman, B. R.; O’Connor, S. E.: Biocatalytic routes to stereo-divergent iridoids. Nature Communications 13, 4718 (2022)

Hong, B.; Grzech, D.; Caputi, L.; Sonawane, P. D.; Rodriguez Lopez, C. E.; Kamileen, M. O.; Hernández-Lozada, N. J.; Grabe, V.; O’Connor, S. E.: Biosynthesis of strychnine. Nature 607, S. 617 - 622 (2022)

Boccia, M.; Grzech, D.; Lopes, A. A.; O’Connor, S. E.; Caputi, L.: Directed biosynthesis of new to nature alkaloids in a heterologous Nicotiana benthamiana expression host. Frontiers in Plant Science 13, 919443 (2022)

Kulagina, N.; Méteignier, L.-V.; Papon, N.; O’Connor, S. E.; Courdavault, V.: More than a Catharanthus plant: A multicellular and pluri-organelle alkaloid-producing factory. Current Opinion in Plant Biology 67, 102200 (2022)

DeMars, M.; Nakamura, Y.; Kamileen, M. O.; Sanders, J. N.; Paetz, C.; Houk, K. N.; O’Connor, S. E.: Mechanism and evolution of [4+2] cyclases in monoterpene indole alkaloid biosynthesis. Faseb Journal 36 (S1) (2022)

Rodriguez Lopez, C. E.; Jiang, Y.; Kamileen, M. O.; Lichman, B. R.; Hong, B.; Vaillancourt, B.; Buell, C. R.; O’Connor, S. E.: Phylogeny-aware chemoinformatic analysis of chemical diversity in Lamiaceae enables iridoid pathway assembly and discovery of aucubin synthase. Molecular Biology and Evolution 39 (4), msac057 (2022)

Koudounas, K.; Guirimand, G.; Hoyos, L. F. R.; Carqueijeiro, I.; Cruz, P. L.; Stander, E.; Kulagina, N.; Perrin, J.; Oudin, A.; Besseau, S. et al.; Lanoue, A.; Atehortùa, L.; St-Pierre, B.; Giglioli-Guivarc’h, N.; Papon, N.; O’Connor, S. E.; Courdavault, V.: Tonoplast and peroxisome targeting of gamma-tocopherol N-methyltransferase homologs involved in the synthesis of monoterpene indole alkaloids. Plant and Cell Physiology 63 (2), pcab160, S. 200 - 216 (2022)

Courdavault, V.; O’Connor, S. E.; Jensen, M. K.; Papon, N.: Metabolic engineering for plant natural products biosynthesis: new procedures, concrete achievements and remaining limits. Natural Product Reports 38 (12), S. 2145 - 2153 (2021)

Yamamoto, K.; Grzech, D.; Koudounas, K.; Stander, E. A.; Caputi, L.; Mimura, T.; Courdavault, V.; O’Connor, S. E.: Improved virus-induced gene silencing allows discovery of a serpentine synthase gene in Catharanthus roseus. Plant Physiology 187 (2), S. 846 - 857 (2021)

Bat-Erdene, U.; Billingsley, J. M.; Turner, W. C.; Lichman, B. R.; Ippoliti, F. M.; Garg, N. K.; O’Connor, S. E.; Tang, a. Y.: Cell-free total biosynthesis of plant terpene natural products using an orthogonal cofactor regeneration system. ACS Catalysis 11 (15), S. 9898 - 9903 (2021)

Brose, J.; Lau, K. H.; Dang, T. T. T.; Hamilton, J. P.; do Vale Martins, L.; Hamberger, B.; Hamberger, B.; Jiang, J.; O’Connor, S. E.; Buell, C. R.: The Mitragyna speciosa (Kratom) Genome: a resource for data-mining potent pharmaceuticals that impact human health. G3: Genes, Genomes, Genetics 11 (4), jkab058 (2021)

Carqueijeiro, I.; Koudounas, K.; de Bernonville, T. D.; Sepúlveda, L. J.; Mosquera, A.; Bomzan, D. P.; Oudin, A.; Lanoue, A.; Besseau, S.; Cruz, P. L. et al.; Kulagina, N.; Stander, E. A.; Eymieux, S.; Burlaud-Gaillard, J.; Blanchard, E.; Clastre, M.; Atehortùa, L.; St-Pierre, B.; Giglioli-Guivarc’h, N.; Papon, N.; Nagegowda, D. A.; O’Connor, S. E.; Courdavault, V.: Alternative splicing creates a pseudo-strictosidine beta-D-glucosidase modulating alkaloid synthesis in Catharanthus roseus. Plant Physiology 185 (3), S. 836 - 856 (2021)